• Antibiotic prescribing in children with reported penicillin or cephalosporin allergy
    www.rch.org.au/clinicalguide/guideline_index/Antibiotic_prescribing_in_children_with_reported_penicillin_or_cephalosporin_allergy/
    from an alternate β-lactam class Drug allergy testing (drug challenge or skin testing) should take … the reported reaction) Past history of other drug and non-drug allergies Atopic disease Examination No specific … or drug-induced liver injury: discuss with local paediatric team or drug allergy service Safe to prescribe all non …
  • Anaphylaxis
    www.rch.org.au/clinicalguide/guideline_index/Anaphylaxis/
    symptoms typically by 30 minutes Oral medication (drug) allergy are slower usually occurring in 1-6 hours …: Hospital Management of Cardiopulmonary Arrest Key points The World Allergy Organization Anaphylaxis …, co-existing anxiety) or after consultation with a paediatric allergy specialist in special circumstances (eg …
  • Urticaria
    www.rch.org.au/clinicalguide/guideline_index/Urticaria/
    infection rather than an allergy to the antibiotic. Take a detailed  drug allergy history  and consider … specialist drug allergy clinic referral Other causes   Contact and irritant dermatitis (eg to plants, animals … C1 esterase inhibitor deficiency IgE-mediated food allergy Serum Sickness and Serum Sickness like …
  • Rhinitis and rhinosinusitis
    www.rch.org.au/Persistent_nasal_discharge_rhinosinusitis/.aspx
    Postnasal drip Loss of smell Cough Halitosis Exposure to cigarette smoke Adenoid hypertrophy Allergy Asthma … with menstrual cycle, pregnancy Subclinical hypothyroidism in older children Drug induced Typically aspirin … if penicillin allergy) If not improving, Amoxicillin/clavulanic acid 22.5 mg/kg (max 875 mg) oral 12 hourly …
  • Serum Sickness and Serum Sickness like reactions (SSLRs)
    www.rch.org.au/clinicalguide/guideline_index/Serum_Sickness_and_Serum_Sickness_like_reactions_(SSLRs)/
    is lifesaving, or no suitable alternative exists – refer to clinical pharmacology or paediatric drug allergy … and rabbit anti-thymocyte globulin (ATG) Monoclonal antibody drugs such as Rituximab are most often … immune-complex formation. They are triggered by a variety of drugs, most commonly cefaclor and amoxicillin …
  • Local anaesthetic poisoning
    www.rch.org.au/clinicalguide/guideline_index/Local_anaesthetic_poisoning/
    Adverse events reported after lipid emulsion infusion: Allergy and anaphylaxis Interference … poisoning: Referral to YoDAA, Victoria's Youth Drug and Alcohol Advice service: 1800 458 685   Information … are kept in the central drug room in the emergency department as well as in theatre.   Information Specific …
  • Vancomycin
    www.rch.org.au/clinicalguide/guideline_index/Vancomycin/
    reaction in patient notes and update their Allergies and Adverse Drug Reaction details Infuse subsequent …, the AUC is not required to be calculated Dosing regimens Patient age Dosing regimen   Therapeutic drug … a loading dose when switching to a continuous infusion Therapeutic drug monitoring Target exposure …
  • Vomiting
    www.rch.org.au/clinicalguide/guideline_index/Vomiting/
    intestinal Diarrhoea Gastroenteritis Associated with certain food ingestion Non-IgE mediated food allergy …, polydipsia DKA Toxidromes, possible toxin ingestion, drug use Poisoning Alcohol Cannabis hyperemesis Neonate …
  • Intravenous access - Peripheral
    www.rch.org.au/clinicalguide/guideline_index/Intravenous_access_Peripheral/
    cannulation Use sterile gloves if midlines or long cannulas are being inserted Refer to Latex allergy … Running a 'drug line' (3-5 mL/hr of sodium chloride 0.9%) through the cannula may keep it patent … unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies. Mayo Clin Proc …
  • Acute otitis media
    www.rch.org.au/clinicalguide/guideline_index/Acute_otitis_media/
    . Recent Patents on Inflammation & Allergy Drug Discovery. 2017. 11 (1), p32 – 40. [Available from https …