• Selective serotonin re-uptake inhibitors SSRIs poisoning
    www.rch.org.au/clinicalguide/guideline_index/Selective_serotonin_re-uptake_inhibitors_SSRIs_poisoning/
    with benzodiazepines). Citalopram or escitalopram overdose can cause cardiac dysrhythmias (wide complex bradycardia … monitoring and serial ECG if large citalopram or escitalopram ingestion, duration of monitoring will depend … be treated with titrated intravenous benzodiazepines (discuss with toxicologist) Treat seizures …
  • Cannabis withdrawal syndrome
    www.rch.org.au/clinicalguide/guideline_index/Cannabis_withdrawal_syndrome/
    in cannabis use Around one in six young people who ever use cannabis may develop symptoms of dependence … for treatment not related to cannabis use  Most dependent cannabis users have concurrent dependence to nicotine …, cocaine, MDMA), benzodiazepines, opioids (heroin, prescription opioids), inhalants (nitrous oxide/‘nangs …
  • Seizures - acute management
    www.rch.org.au/clinicalguide/guideline_index/Seizures_-_acute_management/
    minutes or unknown Include pre-hospital doses of benzodiazepines in active management Ensure parental … benzodiazepine doses given to treat the seizure immediately prior to arrival at hospital Past history: previous … Age: treatable cause is more likely in children <6 months Consider pyridoxine dependent seizures …
  • Serotonin and noradrenaline re-uptake inhibitors SNRIs poisoning
    www.rch.org.au/clinicalguide/guideline_index/Serotonin_and_noradrenaline_re-uptake_inhibitors_SNRIs_poisoning/
    and tapentadol have weak SNRI effect) The risk of seizures following overdose with SNRIs is dose dependent … seizures with benzodiazepines Avoid phenytoin and fentanyl  4.  Serotonin Syndrome Hyperthermia is a sign … with titrated intravenous benzodiazepines (Discuss with toxicologist) Ongoing care and monitoring Because …
  • Serotonin toxicity
    www.rch.org.au/clinicalguide/guideline_index/Serotonin_toxicity/
    and paracetamol concentration in deliberate self-poisoning Depending on severity further investigations may …, troponin Depending on the drug/agent ingested further investigations may be needed (Discuss … and mental status Serotonin toxicity can be treated with titrated intravenous benzodiazepines in discussion …
  • Antihistamine poisoning
    www.rch.org.au/clinicalguide/guideline_index/Antihistamine_poisoning/
    co-ingestions depending on the formulation, such as paracetamol levels. For 24 hour advice, contact … protection.  Discuss with toxicologist. Seizures or severe agitation should be treated with benzodiazepines …
  • Substance use (abuse)
    www.rch.org.au/clinicalguide/guideline_index/Substance_use_abuse/
    and behavioural reaction to a drug depends on: characteristics of the individual (eg age, size, gender, health … withdrawal, benzodiazepine withdrawal or stimulant intoxication.   See  seizure management Disposition …
  • Anticholinergic syndrome
    www.rch.org.au/clinicalguide/guideline_index/Anticholinergic_syndrome/
    severity of symptoms and signs is generally dose dependent. Mild Anticholinergic Toxicity Moderate … crystalloid bolus. Treat seizures with benzodiazepines Treat hypoglycaemia Treat hyperthermia with cooling … will reveal the need for a urinary catheter. The use of decontamination / enhanced elimination depend …
  • Risperidone Poisoning
    www.rch.org.au/clinicalguide/guideline_index/Risperidone_Poisoning/
    can vary depending on an individual’s metabolism, from 3–30 hours)  Children requiring assessment Any … treatment Seizure: administer IV benzodiazepines; add propofol or barbiturates if seizures recur or persist …
  • Local anaesthetic poisoning
    www.rch.org.au/clinicalguide/guideline_index/Local_anaesthetic_poisoning/
    in the systemic circulation.  This in turn depends on a number of factors, including Total dose Rate …; AVOID calcium channel blockers, beta blockers, local anaesthetics Treat seizures with benzodiazepines …