In this section
Poisoning – acute guidelines for initial management
For 24 hour advice, contact the Poisons Information Centre 13 11 26
Risperidone is an atypical antipsychotic that is a selective monoaminergic antagonist with strong affinity for serotonin type 2 (5-HT2) receptors and slightly weaker affinity for dopamine type 2 (D2) receptors.
Risperidone blocks dopamine receptors resulting in extrapyramidal symptoms. Alpha-1 adrenergic effects are responsible for orthostatic hypotension. Its affinity, albeit low, for histamine receptors contributes to anticholinergic effects.
Toxicity usually manifests within 4 hours
Mild to moderate toxicity:
Always check for Medicalert bracelet in any unconscious patient, or any other signs of underlying medical condition (fingerprick marks etc)
3. Specific treatment
Admission should be considered for
For emergency advice and paediatric or neonatal ICU transfers, see Retrieval Services.
Parent Information: Poisoning prevention for children
Prevention of poisoning (Victorian Poisons Information Centre)
Poisons Information Centre: phone 13 11 26
Poisons Information Centre
Child & Adolescent Mental Health Services (CAMHS): Victorian government mental health services are region-based
Orygen Youth Health: Specialist mental health services for people aged 15–25 years, residing in the western and north-western regions of metropolitan Melbourne. Triage/intake - 1800 888 320.
Headspace: National Youth Mental Health Foundation with local headspace centres
YSAS (Youth Support and Advocacy Service): Outreach teams across Melbourne and regional Victoria for young people experiencing significant problems with alcohol and/or drug use
YoDAA: Victoria’s Youth Drug and Alcohol Advice service - provides information and support for youth AOD needs or anyone concerned about a young person
Infoxchange Service Seeker: Search for local community support services e.g. local doctor, dentist, counselling services, drug and alcohol services.
Last Updated September 2020