Primary Care Liaison

Diarrhoea - chronic non bloody

  • Introduction

    This guideline relates to inflammatory bowel disease in paediatric patients. For more information please see: Clinical Practice Guidelines: Abdominal pain - acute or Clinical Practice Guidelines: Abdominal pain - chronic

    When to refer

    • Patients aged 0-16 years
    • Suspected inflammatory bowel disease where chronic diarrhoea (non-bloody) or other symptoms > 4 weeks with elevated faecal calprotectin (> 100 mcg/g), and no other critical features (non-urgent <90 days)
    • Suspected or known inflammatory bowel disease where chronic diarrhoea (bloody or non-bloody) or other symptoms > 4 weeks with elevated faecal calprotectin (> 250 mcg/g), and any of the following critical features are present (urgent):
      • New progressive gastrointestinal symptoms (e.g. abdominal pain, vomiting)
      • Faltering growth (weight loss of > 2 weight centiles)
      • Perianal pain or fistulae suspected
      • Laboratory critical feature:
        • Anaemia
        • Low albumin
        • Elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP)
        • Iron deficiency
        • Holotranscobalamin (active vitamin B12) deficiency
      • Abnormal imaging suggesting inflammatory bowel disease 

    Note: faecal calprotectin levels can be elevated in healthy, pre-school aged children and should be interpreted with caution 

    • Known inflammatory bowel disease with a flare of symptoms
    • Known inflammatory bowel disease for routine follow-up
    If any of the following are present or suspected, please direct the patient to the Emergency Department (no referral required):
    • Suspected or known inflammatory bowel disease with severe abdominal pain and/or bloody diarrhoea, and any of the following features:
      • Fever
      • Haemodynamic compromise
      • Suspected megacolon  
      • Suspected bowel perforation
      • Bowel obstruction
      • Abscess (abdominal or perianal)
      • Haemoglobin < 90 g/L

    Services available closer to home

    Other hospitals with public paediatric general medicine/gastroenterology services include:

    • Austin Hospital
    • Box Hill Hospital (Eastern Health)
    • Monash Medical Centre
    • The Northern Hospital
    • Sunshine Hospital (Western Health)

    Referral criteria/required information

    • Detailed history and assessment, including duration of symptoms
    • Family history of inflammatory bowel disease
    • Provisional diagnosis and current management to date  
    • Growth charts: including current weight, weight loss (amount and timeframe)
    • Blood tests:
      • C-reactive protein (CRP)
      • Erythrocyte sedimentation rate (ESR)
      • Full blood count (FBC)
      • Iron studies
      • Liver function test results
      • Holotranscobalamin (active vitamin B12)
    • Stool sample
      • Stool microscopy, multiplex PCR and Clostridium difficile toxin
      • Faecal calprotectin result (in children aged > 4 years)
    • Any previous investigations e.g., x-ray, ultrasound
    • Current and previous colonoscopy results

    How to refer

    RCH Specialist Clinics Referral.pdf

    Please complete the above and submit via:

    • Fax (03) 9345 5034 or
    • Email screferrals@rch.org.au
    • Urgent referral or clinical query call ED admitting officer or Gastroenterology Outpatient Consult Fellow (03) 9345 5522. If after hours ask for Gastroenterology fellow on call

    Information for families

    Resources and links

    Acknowledgements

    The development of this guideline was coordinated by the Department of Gastroenterology (A/Prof. George Alex). Guideline reviewed in July 2025.