Senior neurologist

Director of RCH Global

Biographical Sketch

A/Prof Andrew Kornberg is a paediatric neurologist with considerable neuromuscular experience.  He completed  Paediatric Neurology and Neuromuscular Fellowships in the United States working in St Louis, USA.  He has had extensive laboratory and clinical experience in immune-mediated neurologic syndromes, including Guillain-Barré syndrome, Miller Fisher syndrome, multifocal motor neuropathy, chronic inflammatory demyelinating polyneuropathy (CIDP), childhood multiple sclerosis and acute disseminated encephalomyelitis.

Clinical Interests

As Director of both Neurology at the Royal Children's Hospital (RCH), and of the National Muscular Dystrophy Centre at the Howard Florey Institute, Andrew has been able to continue clinical and laboratory research.  The two positions have been very productive with national and international grants being received from the NHMRC and the USA MDA for research into novel genetic therapies in muscular dystrophy.  Andrew's neuromuscular interest has meant that RCH has become a member of the Cooperative International Neuromuscular Research Group.  This is a consortium of researchers developing treatments for the muscular dystrophies.

Andrew has a strong interest in immune-mediated neurologic syndromes, including childhood MS, Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy (CIDP).  This interest has led him to be the Chairman of an Asia-Pacific IVIG Advisory board.  He is in the process of organising The IVIG in Neurological Disease: 1st Asia Pacific Symposium (INDAPS) conference to be held in Singapore.

Research Interests

Andrew has major clinical and laboratory research interests in the muscular dystrophies, and immune-mediated neurologic syndromes.

Selected publications

1. Kornberg AJ. Clinical experience with IVIG for treatment of pediatric GBS and CIDP. In: Dalakas MC, Späth PJ, editors. Intravenous Immunoglobulins in the Third Millenium. London: The Parthenon Publishing Group, 2004: 181-185.
2. Byrne E, Kornberg AJ, Kapsa R. Duchenne muscular dystrophy: hopes for the sesquicentenary. Med J Aust 2003;179:463-464.
3. Kornberg AJ. Guillain-Barré syndrome, variants and related syndromes. Practical Immunology.  2003. Honolulu, Hawaii USA, American Academy of Neurology Annual Meeting.
4. Kapsa RMI, Kornberg AJ, Byrne E. Novel therapies for Duchenne muscular dystrophy. Lancet Neurology 2003;2:299-305.
5. Kapsa RMI, Wong SHA, Bertoncello I et al. CD45 fraction bone marrow cells as potential delivery vehicles for genetically corrected dystrophin loci. Neuromuscul Disord 2002;12 (Suppl 1):S61-S66.
6. Rodriguez-Casero MV, Shield LK, Coleman LT, Kornberg AJ. Childhood chronic inflammatory demyelinating polyneuropathy with CNS demyelination resembling MS. Neuromuscul Disord 2003;13:158-161.
7. Hynson JL, Kornberg AJ, Coleman LT et al. Clinical and neuroradiological features of acute disseminated encephalomyelitis. Neurology 2001;56:1308-1312.
8. Kornberg AJ. Anti-GM1 ganglioside antibodies: their role in the diagnosis and pathogenesis of immune-mediated motor neuropathies. J Clin Neurosci 2000;7:191-194.

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