The Royal Children's Hospital (RCH) Children's Cancer Centre (CCC) is the largest partner in the Victorian Paediatric IntegratedCancer Services (PICS) and is a memebr of theVictorian Comprehensive Cancer Care program    The CCC is the only provider of complex children's cancer care and stem cell transplantation in the State of Victoria. The CCC is recognised as an international leader in the research and treatment of childhood cancer, each year treating around 180 newly diagnosed cancer patients under the age of 18 and many children receive ongoing treatment and/or active patient follow up.

The CCC aims for the highest standards in diagnosis, research, treatment, and support. The RCH CCC comprises: an inpatient ward with designated bone marrow transplant beds; a day oncology unit; outpatient clinic area including allied health facilities; a dedicated oncology pharmacy; a family facility; a research program with state-of-the-art laboratory facilities;a clinical trials office and an administrative centre.

The CCC has affiliations with the University of Melbourne, the Murdoch Children's Research Institute and the community. The CCC actively participates in cancer clinical trials and is a full member of the Children's Oncology Group (COG).