Reference |
Source of Evidence
|
Key
findings and considerations |
Brouwer, M., McIntyre, P., Prasad, K., & van de Beek, D. (2015) Corticosteroids for acute bacterial meningitis. Cochrane Database of Systematic Reviews, 9. doi: 10.1002/14651858.CD004405.pub5
|
Retrospective Study
|
Corticosteroids significantly reduced hearing loss and neurological sequelae, but did not reduce overall mortality. Data support the use of corticosteroids in patients with bacterial meningitis in high‐income countries. We found no
beneficial effect in low‐income countries.
|
Children’s Minnesota ED Guideline. Suspected
Meningitis. https://www.childrensmn.org/References/cds/meningitis-protocol.pdf
|
Clinical Guideline
|
Assessment and management of suspected meningitis
|
Fenton-Jones, M., Cannon, A., & Paul, S. (2017) Recognition and nursing management of sepsis in early infancy
. Emergency Nurse. 25(6), 23-28. doi: 10.7748/en.2017.e1704
|
Recommendation from Authoritative Bodies
|
The clinical features of neonatal sepsis can be non-specific and varied, and neonates are vulnerable to infections due to their immature immune systems. Consequently, when triaging ill infants, neonatal sepsis is an important differential
diagnosis to consider. ED nurses play an important role in the identification and management of neonatal sepsis, and NICE (2012, 2016) recommends taking a thorough history and
examination, appropriate investigations, and administrating antibiotics. ED nurses also play an essential role in monitoring neonates’ condition and supporting families.
|
Hickey, J. (2014) Clinical Practice of Neurological & Neurosurgical Nursing (7th ed.). Wolters Kluwer Health; Philadelphia, PA. |
Textbook
|
Nursing patients in low stimulus environments.
Positioning of child in bed.
|
Hockenberry, M.J. (2019). Wong’s Nursing Care of Infants and Children, (11t ed.) https://www.clinicalkey.com/student/nursing/content/toc/3-s2.0-C20160013463 |
Textbook |
Nursing responsibilities for the treatment of meningitis
|
Hsieh, D.-Y., Lai, Y.-R., Lien, C.-Y., Chang, W.-N., Huang, C.-C., Lu, C.-H., Cheng, B.-C., & Kung, C.-T. (2021). Nationwide population-based epidemiological study for outcomes of adjunctive steroid therapy in pediatric patients with
bacterial meningitis in taiwan. International Journal of Environmental Research and Public Health, 18(12). https://doi.org/10.3390/ijerph18126386 |
Retrospective study |
Reduction in hearing impairment with the use of corticosteroids in patients with Haemophilus influenzae type b (Hib) meningitis but not in patients with non- haemophilus infections
|
Maconochie, I., & Bhaumik, S. (2016) Fluid therapy for acute bacterial meningitis. Cochrane Database of Systematic
Reviews. doi: 10.1002/14651858.CD004786.pub5. |
Retrospective Study
|
Fluid therapies in suspected or confirmed meningitis
|
National Institute for Health and Care Institute. (2018) Bacterial meningitis and meningococcal septicaemia in
under 16s: recognition, diagnosis and management. https://www.nice.org.uk/guidance/cg102
|
Clinical Guideline
|
- Recognising bacterial meningitis
- Investigations for suspected bacterial meningitis
- Antibiotics
- Investigations
-
Follow-up care
|
Odeh, C. E. (2020). An Infant’s Recovery from Bacterial Meningitis: Navigating Care Internationally.
Indian Journal of Physiotherapy & Occupational Therapy.14(2), 249–253. https://doi.org/10.37506/ijpot.v14i2.2657 |
Retrospective study |
Risk factors for infants, children susceptibility to meningitis; low birth weight, cochlear implants, infants with hypotension.
|
Ogunlesi, T., Odigwe, C., & Oladapo, O. (2015) Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis. Cochrane Database of Systematic Reviews. doi: 10.1002/14651858.CD010435.pub2.
|
Retrospective Study |
Very low‐quality data from two randomised controlled trials suggest that some reduction in death and hearing loss may result from use of adjunctive steroids alongside standard antibiotic therapy for treatment of patients with neonatal
meningitis. Benefit is not yet seen with regards to reduction in neurological sequelae
|
Ramasamy R, et al. (2018) Management of suspected paediatric meningitis: A multicentre prospective cohort study.
Archives of Disease in Childhood. (103) 1114-1118. doi:10.1136/archdischild-2017-313913
|
Prospective Cohort Study |
Quantifying delays during management of children with suspected meningitis.
Source of assessment and monitoring information.
Patients with sepsis reported fourfold increased odds of mortality for antibiotic delay greater than 3hours from sepsis recognition. In children who survive bacterial meningitis, delaying antibiotic treatment over 24hours from symptom onset is associated
with persistent neurological sequelae. UK guidelines therefore recommend administering parenteral antibiotics without delay for children with suspected bacterial meningitis and within 1hour for children with high risk of sepsis.
|
Swanson, D. (2015) Meningitis. Pediatrics in
Review. 35(12), 514-524. doi: 10.1542/pir.36-12-514 |
Journal Article
|
Discusses causes, clinical manifestations and general approaches to diagnosis, treatment, and prevention.
Understanding indications for neuroimaging, adjunctive corticosteroids, and LPs.
Recognizing complications and sequelae of bacterial meningitis
Source of assessment and monitoring information
|
The Royal Children’s Hospital Clinical Practice Guideline. Meningitis –
Encephalitis (state-wide). https://www.rch.org.au/clinicalguide/guideline_index/Meningitis_Guideline/
|
Clinical Guideline |
Risk factors, management and treatment of meningitis
|
The Royal Children’s Hospital Kids Health Info Fact Sheet. Meningitis. https://www.rch.org.au/kidsinfo/fact_sheets/Meningitis/
|
Recommendations from Authoritative Bodies
|
Signs and symptoms of meningitis and follow up
|