Hand, foot and mouth disease

  • Hand, foot and mouth disease (HFMD) is a viral infection that causes a rash or blisters on the hands and feet, as well as in or around the mouth. There are two types of viruses that cause HFMD, and the symptoms vary depending on the virus.

    HFMD mainly affects children under the age of 10, but can also affect adolescents. It spreads easily from one person to another. It is possible to contract the virus more than once, but the symptoms will be less severe.

    HFMD is not related to the foot and mouth disease that is found in animals.

    Signs and symptoms of HFMD

    Symptoms usually start three to seven days after becoming infected, and can last from seven to 10 days. If your child has HFMD, they may feel tired, have a fever, and have a rash. Depending on which virus your child has, the skin rash can look like:

    • Small, oval, white blisters on the palms, soles of the feet, as well as in the mouth. Your child may have a sore mouth and throat, leading to poor appetite or risk of dehydration (drinking and eating can be painful because of the mouth blisters).
    • A red skin rash with a brown scale on it. The rash appears on the outer arms, hands, legs, feet, around the mouth and upper buttocks. The trunk is usually relatively clear. Sometimes there are blisters present, but they are not usually in the mouth and your child can eat and drink as usual.

    The blisters should not be itchy like chickenpox blisters. If your child has eczema, the HFMD can cause the eczema to worsen and potentially become infected with bacteria.

    HFMD foot

    How is HFMD spread?

    HFMD is most commonly caused by the coxsackie virus. The main way HFMD spreads is through contact with the fluid from inside the blisters, or with the droplets spread from sneezing and coughing. The virus can also be present in bowel movements (poo) for up to several weeks after the person has recovered.

    To prevent the spread of HFMD:

    • Wash your hands thoroughly after touching your child’s bodily fluids. This includes touching their blisters, helping them blow their nose, and changing nappies or helping with toileting.
    • Make sure your child doesn’t share items such as cutlery, drinking cups, towels, toothbrushes and clothing.
    • Keep your child home from school, kindergarten or child care until all the fluid in their blisters has dried.

    Care at home

    HFMD is a viral infection that rarely causes further complications. Antibiotics do not work on viruses and are not given to children with HFMD. HFMD will get better on its own, but there are ways you can care for your child at home:

    • If your child is in pain or is uncomfortable, give them pain relief, such as paracetamol or ibuprofen. Do not give aspirin. See our fact sheet Pain relief for children.
    • Give your child frequent sips of water or an oral rehydration solution to stop them becoming dehydrated.
    • Leave blisters to dry naturally. Do not pierce or squeeze them.
    • If your child is unwell with a fever and a skin rash (small bright red spots or purple spots or unexplained bruises) that does not turn to skin-colour (blanch) when you press on it, this may be a sign of meningococcal infection (see our fact sheet Meningococcal infection).

    Key points to remember

    • HFMD is a mild illness that will get better on its own.
    • Two types of viruses cause HFMD, and the rash depends on which virus your child has.
    • HFMD is spread easily from one person to another.

    For more information

    Common questions our doctors are asked

    Is HFMD dangerous for pregnant women?

    HFMD is not known to pose a risk to pregnant women or their unborn babies.

    My child still has blisters. Can she return to school?

    If the fluid in the blisters has dried, then it is safe for your child to go back to school.

    Developed by The Royal Children's Hospital Emergency and Infection Control departments. We acknowledge the input of RCH consumers and carers.

    Reviewed February 2018.

    This information is awaiting routine review. Please always seek the most recent advice from a registered and practising clinician.

    Kids Health Info is supported by The Royal Children’s Hospital Foundation. To donate, visit www.rchfoundation.org.au.


This information is intended to support, not replace, discussion with your doctor or healthcare professionals. The authors of these consumer health information handouts have made a considerable effort to ensure the information is accurate, up to date and easy to understand. The Royal Children's Hospital Melbourne accepts no responsibility for any inaccuracies, information perceived as misleading, or the success of any treatment regimen detailed in these handouts. Information contained in the handouts is updated regularly and therefore you should always check you are referring to the most recent version of the handout. The onus is on you, the user, to ensure that you have downloaded the most up-to-date version of a consumer health information handout.