In this section
Congenital hyperinsulinism (HI) is a rare genetic disorder in which the insulin cells of the pancreas, called beta cells, secrete too much insulin. Excess insulin causes low plasma sugar (hypoglycaemia).
The treatment for this condition is to try and maintain blood sugars greater than 3.5 mmol/L. There are two long-term options for treatment of congenital hyperinsulinism, usually with medical therapy as first line treatment (e.g. supplementing feeds, diazoxide, octreotide) and surgical intervention in select patients (e.g. focal lesion) or those who fail medical therapy.
Please refer to the RCH clinical practice guideline for general management of hypoglycaemia and critical samples.
Exeter genetic testing for hyperinsulinism
NIH Congenital hyperinsulinism information page
Hypoglycaemia management plan
School management plan
Refer to diabetes educational videos for:
How to do a finger prick check
How to give glucagon
Blood glucose monitoring module (please refer to your management plan regarding blood glucose target levels for your children's condition)