In this section
Note: this is a past research project that is now complete.
There is a striking lack of information examining
community-based case-control studies of adolescent depression. The
aim of this study was to investigate a range of risk factors in
young people identified at risk for major depression.
The Victorian Adolescent Health Cohort Study (VAHCS) offered an
outstanding opportunity to mount a case-control study of adolescent
depression. From the second wave of data collection subjects at
high risk for major depression were identified using the Clinical
Interview Schedule (CIS-R). This group of young people were invited
to participate in a second phase interview which included the
depression and hypomania modules of the Comprehensive International
Diagnostic Interview (CIDI). Ninety-three cases of depression and
over 300 non-depressed control subjects were identified in this
study. Interviews were conducted with both parents of identified
cases and a sub-series of controls. Information was collected
covering a broad range of risk factors including parental
psychopathology, previous psychopathology and health risk
behaviour, pre-morbid personality, childhood temperament, childhood
separations and illness and parental bonding.