Benzodiazepine poisoning

  • See also

    Poisoning - Acute Guidelines for initial management

    Often taken as part of mixed overdose in adolescents


    • CNS depression, drowsiness, coma
    • Respiratory depression
    • Hypotension
    Beware additive toxicity with other CNS & Respiratory depressants

    Patients requiring observation

    • Ingestion of gte sign3 times recommended dose for age
    • All symptomatic patients
    • Ingestion of unknown quantity


    • Charcoal is not usually of benefit (due to low order of toxicity)
    • If depressed state of consciousness, protect airway and contact ICU (5212)
    • Antidote available - Flumazenil, not indicated for ingestions and should only be used after discussion with consultant staff.