In this section
This guideline describes the processes for requesting, administering, and monitoring buffy coat granulocyte infusions at The Royal Children’s Hospital for relevant oncology, haematology and immunology patients.
If ongoing continue 30 minutely observations
Volume of granulocytes X drop factor
of line (e.g., 20 drops/mL) = n drops/minute
Time for infusion in minutes
To adjust the rate, use the roller clamp to regular to infuse at the desired rate, will need to count the drops/minute for a full minute.
Note: the product can be viscous and difficult to infuse, regular flushing or use of a giving set with normal saline and gentle agitation of the product may help maintain the flow rate.
Note: Administer separately to amphotericin B: there must be at least 2 hours between amphotericin B and granulocyte infusions as there may be an increased risk of pulmonary reactions in patients receiving granulocytes with amphotericin B.