Australian Paediatric Pharmacology Research Unit (APPRU)

APPRU Services

  • Research

    Protocol development

    APPRU staff have experience with protocol development. Protocols are developed to ensure all studies are carried out in accordance with the National Health and Medical Research Coucil (NHMRC) National Statement on Ethical Conduct in Research Involving Humans, The Declaration of Helsinki and Therapeutic Goods Administration (TGA) Note for Guidance on Good Clincial Practice (GCP) (CPMP/ICH/135/95).

    Case report forms

    APPRU can assist in CRF development to ensure that all relevant data is collected for analysis of each clinical trial. Staff have extensive experience working with a variety of CRF designs, including electronic formats.

    Recruitment

    Our study participants are drawn from this population as well as a community trial network, through which resources such as general practitioners, maternal and child health nurses, daycare facilities and schools are utilised.

    Clinical trial recruitment officers

    The clinical trial recruitment officers are an APPRU initiative as an acknowledgment of the importance of focused recruitment.

    The clinical trial recruitment officers are responsible for:

    • Assessing the feasibility of proposed studies
    • Design, implementation and evaluation of detailed recruitment strategies
    • Developing new marketing directions for the APPRU

    Links have been established with the following groups and individuals:

    • Paediatricians and Nurses at the Royal Children's Hospital, Melbourne
    • In-patient and out-patient units at the Royal Children's Hospital, Melbourne
    • Metropolitan Maternal & Child Health Nurses
    • Community newspaper groups
    • Metropolitan/State newspaper groups
    • Paediatricians practising in the wider community

    The above links are considered as potential recruitment sources. APPRU values their commitment to paediatric clinical drug trials.

    Study evaluation

    The APPRU staff are skilled in evaluating study protocols to assess their feasibility and to identify any potential problems in the study which may hinder the recruitment process if the studies are too difficult.

    Facilities

    A purpose-built clinical trials area is now well established. We provide a non-threatening and family friendly environment to clinical trial participants in both inpatient and outpatient settings.

    Our area contains:

    • Kitchen facilities
    • 3 exam / treatment rooms (exam beds/cots, sphygmomanometer, writing desk)
    • A large treatment area / patient lounge
    • Fully stocked resuscitation trolley
    • Pathology processing area
    • Refrigerated centrifuge (Maintenance details available on request)
    • -80oC Freezer (Temperature and maintenance logs available on request)
    • Monitored 2-8 degree celcius refrigerator

    To learn more about our facility please see our room manual.

    To view current bookings for these rooms click here. To make a booking contact Shannon Kokoszka shannon.kokoszka@rch.org.au for further information.