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Diagnostics

  • Semen Analysis

    The principle of the semen analysis is to assess the macroscopic, and microscopic, quantitative and qualitative, features of an ejaculate. The former examines components; liquefaction, viscosity, appearance, volume and pH. The latter provides an analysis of sperm concentration, sperm motility, sperm velocity, sperm morphology and sperm viability. Other notable elements of a semen analysis include the assessment of leukocytes and prominent morphological defects that may be of a genetic origin.

    Sperm Antibodies IgA and IgG

    The Sperm Mar test (MAR) enables the detection of sperm-bound antibodies of immunoglobulin classes: IgG and IgA. The MAR can be used either as a "direct" test for detecting antibodies bound to a patient's spermatozoa in seminal fluid, or as an "indirect" test for detecting sperm antibodies in serum or various reproductive tract fluids.  

    Seminal Fructose

    Fructose is qualitatively assessed for presence or absence in seminal plasma using a simple colour change test. The Seliwanoff assay is utilised for this test.   

    Semen Oxidative Stress*

    Excessive reactive oxygen species (ROS), produced by both spermatozoa and leukocytes, are normally eliminated effectively by seminal plasma free radical antioxidant scavengers and antioxidant enzymes. Assessing the electropotential of seminal fluid (mV/million sperm/mL) enables the detection of an imbalance in this biological mechanism, and identifies semen samples exhibiting Oxidative Stress.

    *The laboratory is currently performing validation work for this test and it will soon be available as a diagnostic test.