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© Children's Pain Management Service,The Royal Children's Hospital, Melbourne
Local anaesthetics work by blocking nerve impulses on sensory, motor and autonomic nerve fibres. The smallest diameter fibres are most sensitive to the effects of local anaesthetics: autonomic fibres will be blocked first, then sensory fibres and then motor fibres. Motor nerves (as well as sensory nerves) may be affected by local anaesthetics.
Adapted from Epidural Assessment Session, Fremantle Hospital Acute Pain Service, Fremantle, WA, Australia