In this section
For children undergoing HD, incremental IV iron infusion can be given at a dose of Ferrum H 2mg/kg (up to a maximum of 100mg).
A A test-dose should always be given prior to initiating IV iron therapy
Dose for test-dose
The test-dose should be given during the day-time and medical staff must be present during administration and for 15 mins following test-dose. The availability of drugs for treatment of anaphylaxis (adrenaline, hydrocortisone and promethazine) should be readily available (see Adverse Reaction).
Monitor vital signs 15 minutely and observe child closely for 30 minutes for adverse reactions.
The test-dose should be given by slow IV push over 30-60 sec. The remainder of the iron dose should not be given until at least 1 hour after test-dose has been given. If no immediate allergic reactions occur, subsequent routine dosing can be given without a test-dose.
Weekly for 8 weeks then review
Fortnightly for 8 weeks then review
Monthly for 2 months then review
CARI Guidelines 2003
DOQI Guidelines 2000
Pediatric Nephrology (2001) 16: 779-783.