In this section
should always be given prior to initiating IV iron therapy
Dose for test-dose
The test-dose should be given during the
day-time and medical staff must be present during administration
and for 15 mins following test-dose. The availability of drugs for
treatment of anaphylaxis (adrenaline, hydrocortisone and
promethazine) should be readily available (see Adverse Reaction).
Monitor vital signs 15 minutely and observe child closely for 30
minutes for adverse reactions.
The test-dose should be given by slow IV push
over 30-60 sec. The remainder of the iron dose should not be given
until at least 1 hour after test-dose has been given. If no
immediate allergic reactions occur, subsequent routine dosing can
be given without a test-dose.
Weekly for 8 weeks then review
Fortnightly for 8 weeks then review
Monthly for 2 months then review
CARI Guidelines 2003
DOQI Guidelines 2000
Pediatric Nephrology (2001) 16: