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Nephrotic syndrome - pre-referral guideline

Definition

• Proteinuria, Low serum albumin, <25g/l or oedema, elevated cholesterol.</li/>

Initial work-up

• Electrolytes
• Urea
• Creatinine
• Albumin
• Urinalysis with microscopy (clean catch urine)
• FBE
• C3, C4
• Serologic work-up indicated in all patients with multi-system disease: ANA, Hepatitis B, C, ANCA

When to refer

• Refer prior to treatment:
  • All patients with nephrotic syndrome.

• Urgent admission indicated for all patients with nephrotic syndrome.

Information needed

• Bring to clinic visit:
  • Laboratory values

Resources

Kids Connect (RCH Primary Care Liaison)

Kids Health Info (Parent factsheets online)

Contact information                 

References

Paediatric Handbook (2003) Renal conditions and enuresis, Chapter 32 (pp546-566); Colin Jones and Annie Moulden; Seventh Edition, Blackwell Publishing. By the staff of the Royal Children's Hospital, Melbourne, Australia