You can start work on your project once it has received both ethical approval and governance authorisation. It is the responsibility of the Principal Investigator to meet the appropriate submissions and reporting requirements throughout the life of the project. You should make all submissions in Ethics Review Manager (ERM). 

• Amendments – including changes to study team, addition of new sites
  
• Annual and Final Reporting
  
• Safety Reporting
  
• Breaches and Deviations 
• Managing Complaints
• Monitoring Program