Part of the Aorta is absent and this leads to severe obstruction
to blood flow to the lower part of the body.
In the immediate newborn period blood flows through the 'Ductus'
into the Descending Aorta and hence reaches the lower part of the
As the ductus closes
after birth blood pressure in the lower circulation becomes
inadequate and severe symptoms develop.
Most affected infants develop severe symptoms (difficulty
breathing and impaired kidney function) in the first week of life
and need urgent surgery
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