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Transposition of the Great Arteries

• Fact sheet on Transposition
• Fact sheet on Transposition with VSD
• Fact sheet on Transposition with VSD and Pulmonary Stenosis

The Aorta arises from the right ventricle and receives "blue" blood, whilst the Pulmonary Artery arises from the left ventricle. The baby becomes blue immediately after birth and needs urgent treatment. Survival depends on the ductus or the Foramen Ovale remaining open in the early days of life until treatment can be applied. The Foramen Ovale can be enlarged with a catheter procedure, called Balloon Septostomy, which is performed in the first few days of life. This involves a catheter with a balloon at the tip, which is passed from a leg vein until the balloon is in the left atrium (across the Foramen Ovale). The balloon is then inflated and the catheter is pulled back to the right atrium.

Go to Normal Heart

Early surgery is essential and involves the " Arterial Switch Operation", which is carried out in the first week or two of life and corrects the abnormality. The small coronary arteries, which feed the heart muscle with blood, need to be transferred as well as the two Great Arteries (Aorta and Pulmonary Artery).

Until aroud 1980 this delicate surgery could not be performed safely and an alternative procedure was used, redirecting blood within the atriums. This was called a "Senning" operation. (The "Mustard" operation was very similar.)

Senning Operation.

In this operation the blood from the SVC and IVC was redirected to the left atrium and ventricle, while blood from the pulmonary veins was channelled to the right atrium and ventricle.  This relieved Cyanosis but did not correct the original abnormality, leaving the Right Ventricle pumping blood to the Aorta.

Eventually some patients may develop heart failure or other problems after this type of surgery, which is now seldom used.